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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c03c135ef5910d915d20370f098a632b4b20d1dfe47ae67a40fb84a41e1edf56' 
  AND token = 'V4XyqE0UOZTSKmPqUhgaJzc8/miFkczvXH3x3xUWA6o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}