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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca88fe8ee5a4afb2b5a360e2820dfc59c119d3eff752ac42eb8bbb5bc8135df4' 
  AND token = 'TRxwAU6m/pw0Ga6Wo2bmXFopxz6yYNg017tLr0DaDmM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}