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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3bc9e481dbc6e4747c866e261b57a3ba5edaba7fcc10b5856daec8aa6e378f1' 
  AND token = 'u4BoOn7It8k6VVONF4HrH+dF5Qn/7p+/tQWt+343N2w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}