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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '119695237f3b5b6bb1a2a19e3816b46e06dd42e0dc1362a93e0d286dc9305774' 
  AND token = '6vDEXDYRrPkZ+N8dRtAGs1HVlQAUEYArbpgHhhNXIcU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00009

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}