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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '529fe98aed04c2042eb8e4bdef934550c733181fc0508a5ac1bbd1757eaa3dfe' 
  AND token = 'MubOIoJps2+aOC/S6GF9h6hZ4vttPOAazmb25kZJHjs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}