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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16cacec8782047955fd5c4bc3a4e625e0db27c975ed023877c4f663a612a3818' 
  AND token = '2tuAxnuGI5TOnkdpKHqEuJccTtW/u13KC2DJr1LHhRM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}