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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e39b4acd4ab46db7afa3a249f5a3bd7fec52fb3c883dcb623c890fb480e03999' 
  AND token = 'hsNwPInGZbaT+8/8gS7UQtB0Q60PeVIdPvDEa3VBue8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}