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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ef1c47eec88f3969c5e6be54fe338d74967d766226d3b80d102e90e6bb381f0' 
  AND token = 'mIA8XT2FtkTobOdhFIegrbt79UzrtOMT/3tqwVgLa1Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}