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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2d69b187f19a1c14935517f2c1a79fa23d47805f2d6d19d4cf3c60afe979cc4' 
  AND token = 'FJ458d63/IbHWGBzexpyIqmM7ZKc8lTnX6VhHW8iWNM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}