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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac48b7b3d135077e811e02ff21d3fa48c7aaa77b98130ff4f270944827f3f944' 
  AND token = 'bHpvfxVtRzpo0jN8Hu2ittm7BfIl7NF3+FyKpklyoRA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}