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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20a018ccd0926bc9de75359166c9daeb3d3646e9bee7fde0e4cdc4f9e0fcb518' 
  AND token = '7T3weXpU86V/A7AdkpaKKSjbMU5DiAJ4KHvm0CgEy1o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}