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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ebb27c0b552330e028b6fb21cf3bc8c53c758459b740d3e41470a837340c97b8' 
  AND token = 'RpEBNEfcGTRGrrxKA/1V0/oroGI3AjzfGOA5lwxk0CM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}