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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '755d71cfa55d5aebc7c18ebb7368c2f5daaa472a427ccdb2d3edbd0f209d49a3' 
  AND token = 'H6q2qgQQO2HUw7eHD8HKnVXeEs+jL+F+Xnd+LP9AV+0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}