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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c45b81e3d957421a4b0fdd8f5151b2d3fdd06e8fd0b92f263c1eb57d290dcb9' 
  AND token = 'm6IWZq0EP8EmeC4R3aE8vOKRtObDJrSr7YAe2z+hBKY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00065

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}