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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e28a18a7ec1519a3fd345a13f904e93684f52aef8fba414f2357b85315022190' 
  AND token = 'nS7JkClGdeO0X8N/mN5CEXavGeNW0opQJkXOZflK6fs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}