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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11e5a29621755e684431d0fca02d00e46c643df2b33260b4e05c58fa656ee3fd' 
  AND token = 'X0zEEUVJ4gRymSZgG5tQzJQ5G4CNEXCoSSMm+twvvtM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}