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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c784a184ca0568d64adf5ed37a320dae6064b91c0daa25c94dda82e5706114d' 
  AND token = 'QtlhQOO2j56D8K3/oMyX1wFvZIf6RQTfF8NHcIpAkT4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}