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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bd12fc1220357da33b6456ecce6f0ea0ad2cf985b0024ef1821b5d89a421ed58' 
  AND token = 'sys+ih4bLNL8cf+yE57xhNmjeNd26B0PCBm9vaLPl4A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}