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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04d9505cd2736d0eb85f1973c7b81481ba08bd19a63051609efbbd1e15bca19e' 
  AND token = 'NR8LRY+VFXQG0hVjKgND/JWHMAqU9e5UXpMENNlfAlY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00011

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}