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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80468d5dbfb8b5b8fe434c44f5f54b62c833e7f37cca9acec9cdae5e11faa323' 
  AND token = '/YnLclTVU7a2unBfauQZmmrg6O77Z0xFIS2ubZPtaSM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}