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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e12f3f2f1c3017185fb1380f515e51695dcf2c9ddd7d3b717839549216a01e07' 
  AND token = 'V7jY8WkF2fv7Froh5ozCQyTmLQ3B5h0GQ+wuUF2YxiA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}