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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b91b28b3c0b21d9cb6c14e17b3b037bfb1884bea23fa6fd4f05fc107df7648e' 
  AND token = '1GdnyebyDvAPLNO+feTnzSF1lmrz/C5iVXfKwHhtUH0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}