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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11949231a0229f8bebf1e3f3687b223820d419f07a4ab0dd080c1ccea231a6d8' 
  AND token = 'usbs+iDO0d4pv/JIwtYmlJKVLV+CatCabgnKNLwyfEo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}