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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15d4efc935d148446ac267a9d38c7bf857110ffb0102c30f4a7e1d780ac02bce' 
  AND token = 'b3sEiUFp3Lf+E1dto8Iiti+y2XOPqUXzy1BhzwFMRQI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}