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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea01823029b3df5df5dc36f3cf243650e2c5c7b46bcd3386e8e44e3871b0bb73' 
  AND token = '3pWdUTdQiIRly3kJGlDjgjk7ykhr1zbFrvvRrjp6hfQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}