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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6528ad8fd36cca2705cf9c0e6a96cf4ff888020fc66e28994d0a920fc53ac7e6' 
  AND token = 'OR4QB8Mu71TS9eC8iu+1xBEoRKDD3GRlq2d0gFbSjD0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}