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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e05498a7584ca317dcdfee9f4d56e6259429e9da83784e2d10100553e8a5f348' 
  AND token = 'oW8vI94F8zScEUalzgXZByKid2M94kAbAv9GTL8UTXU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}