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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f99a682b1207f9e628297a3740984c698183859b49805b5fdfcde5a18856b87f' 
  AND token = 'uGP4/A6ynxy0FhKht3EXubjFzNdPWMaLPIBDSyfA7YM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}