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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1d5825fd1466d94f2246659f3c5c66e6a0945f07de022c5091787f6c5c4715a' 
  AND token = 'NMIzOwPVaN0ulbOxLb+K6pSb70hGPavKpjOr4eoLtnk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}