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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f44512afdf21b2bd57bd2d64c8583fda884a57ca1cbf9babdc67790a0bc302d' 
  AND token = 'Ek1hSJ5mk8346FVF3+jopYMPf9Jo7ml3dhVdniRkF5M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}