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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3025ca5d27328e71badd9055d67d7022f8c319561463440738890410a1b0134' 
  AND token = 'vomWfGEJdJY57hyiIi759uDPndsy4X1xodFLk7EJDHU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}