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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f631ba946ebc585a17a86f055850c57c471a94e8c903c2428de75c651181a11' 
  AND token = 'D41gEtwM9RKUgUiTTX6pxojZKEDWDfkmQh9tXMY5Rjs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}