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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0f921e8d7f9745ca8b0d749c5481502c64d816ad52e35eec08528238bc74577' 
  AND token = '0GKwHCQw1+PEOnAe7myRDV4xxczBa6ZtpR35HsNtt94=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}