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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea4da15a786133b7afc77263b0c768c4e74ad25344a127fced7a8bcdb0992b1b' 
  AND token = 'sj9RgJ4s2icW/eJws6N8fBYecbP0EFeMrcO4HOuN91U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}