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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04f9b24f6f1002d11a62de0f8585b6a90b98c6eea28425bed22f8aa4373f8e2c' 
  AND token = 'mfdRuRVfJtIQ21vwOKokDKzpF2/rNVu9RhjVm6vNRaA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}