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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a38dc0b44bb4e791cb45ec8164f7e30b29c3e600cf04713112696d1b4eaf2f89' 
  AND token = 'hZAOpC5RwLFscfVimHI7mfrrYOfsfQJ0AULSmbLmFRE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}