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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ab2cd405681af6e4d5ae3f37ee8a48b58e1bd376a842c4fef48f6cd24477125' 
  AND token = 'AKv2vp3l0XEo/dn/b3yR5hkYEEOGFOgkyRgUTu/35to=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}