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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '135b2280169ce2ae0584707b8ce7833bdd99b9468abec8006db7bca9801ea2f7' 
  AND token = '1cmwv2eoSBqXMgbj0m8WwvUc1oPi1jH2nJFoWpZ25VE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}