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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11f5a159e3fd46e2e7385656cefb5fc541bb2871f97f30c7e8c2434676241960' 
  AND token = 'Bwj9SkXCPRvnnB5dLwquYRTZwFNMYMNS4fPrTMmLXdw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}