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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a481053908674e05ede880e203e70f6ca57369209b0c704b70e346d49286308' 
  AND token = 'LNgDdvkfUFz+0tF9gHnb5ph6iKk0fWl4x1ZsIQ3fx8Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}