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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d89029a242846f367b2851600760b621333d5ad512c21488d674406e21b392b' 
  AND token = 'eSmgtEho3X6QcB0Xn0uD+7dYJ8X1fcnlRbacRQ18VU8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}