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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e39f28c9cc3979a6ffbf4b860450cc9aa005ad50a0da797f052e0c034363346' 
  AND token = 'IfYOGw9e1mIw8LdHWcy0WD+sUmheT7xQHSC/dy6qma4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}