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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b77b1998016af2381b301bdb4d174f364a9f7e0fb5ecb0071bde40dd2d9ce99' 
  AND token = 'oCuxoPz6S8JIeIHEsYx+Rr99yHGLCnZU6A/ELS2pkiw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}