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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9bf9f349a3e086a82daea3b071c537643dd3969295616b532bd8214a6ad8f753' 
  AND token = 'fKZZHnMu+/MNnG0FRR+Q6/i6jRFxSXc/Np8j4QmYjio=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}