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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b4fefcb5799fba2985ee2101c03901eb56a87a5468e15c364e8bda2b08180e1' 
  AND token = 'ZLboSYN4htw8lIiRG9CUZjPbz8lXQKBopM9nQ/kKNMw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}