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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '159fb6c46a3c80b8b97eb79aa9dbcdf551fde02891aba9e41a31e2dda1cea932' 
  AND token = 'mLF0Mt7/oAsS6Tgub2eBFFt/8aBMR76Rjrt8UpGSqVQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}