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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7888ae84357078a5587ccfbb053bea25e7e4e2b248bb95a59ae779a79639d01e' 
  AND token = 'BO0TOHz/Jx1Nu78BWE3aBqSJrYlqaS1QJIe4TGFJFGg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}