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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43f21bd530a02620e6b8d2865573b7cc212fb838851ba6919291166072ace3e6' 
  AND token = 'dMtt5os4XpRHD5XL+SeDmHHdbKF4bGzpsowCurd6TrY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}