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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14a85bb1ad9929a0934f7493b9d02542fae860c4cd30b2136eb26db6d9abbddd' 
  AND token = 'X7mH6rUuSlfS+0sUW8sBPHWkdAlP21o4wO1JJwEQ054=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}