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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ca77216c0d6b53c3d360c5989057381d7c502b77938bf8ca35101f67bda3c05' 
  AND token = 'LWll576T0E94bAilZLWaO88V07dqZf4V6T1ihkOzMTQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00011

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}